Biogenic amines – an important group of protein degradation products

A wide diversity of intestinal biogenic amines (BA) -producing and biogenic amines -degrading bacterial species have recently been identified. In short, undigested dietary protein that reaches the colon is fermented by microbes possessing amino acid decarboxylase activity into a range of BAs, along with other degradation products such as phenol, cresol, indole, skatole, ammonia, and branched-chain fatty acids. Many of these protein fermentation products are known to have adverse health effects, and high concentrations of these compounds in the gastrointestinal tract are commonly associated with a wide range of diseases and cancer. Origin of biogenic amines In all life forms, […]